# SPG7 maybe the cause of Late Onset Ataxia

**URL:** <https://forum.livingwithataxia.org/t/spg7-maybe-the-cause-of-late-onset-ataxia/6936>\
**Category:** General\
**Created:** [August 22, 2018, 11:52am UTC](https://forum.livingwithataxia.org/t/spg7-maybe-the-cause-of-late-onset-ataxia/6936 "2018-08-22T11:52:26Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![Alan\_T](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.livingwithataxia.org/alan_t/32/31_2.png) [@Alan\_T](https://forum.livingwithataxia.org/u/Alan_T)\
**Post date:** [August 22, 2018, 11:52am UTC](https://forum.livingwithataxia.org/t/spg7-maybe-the-cause-of-late-onset-ataxia/6936/1 "2018-08-22T11:52:26Z")

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[#SPG7]([https://twitter.com/search?q=%23](https://twitter.com/search?q=%23)

SPG7) c.1529C\>T (p.Ala510Val) mutants account for 2.3% of [#cerebellar](https://twitter.com/search?q=%23cerebellar) ataxia cases in Italy, suggesting that this variant should be considered as priority test in the presence of late onset pure [#ataxia](https://twitter.com/search?q=%23ataxia) [onlinelibrary.wiley.com/doi/abs/10.111…](https://t.co/MNiz1ZoRc2)

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**Author:** ![manjad](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.livingwithataxia.org/manjad/32/5001_2.png) [@manjad](https://forum.livingwithataxia.org/u/manjad)\
**Post date:** [August 28, 2018, 9:06am UTC](https://forum.livingwithataxia.org/t/spg7-maybe-the-cause-of-late-onset-ataxia/6936/2 "2018-08-28T09:06:29Z")

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Very Interesting! I was only tested for SCA6 as that was the only one that applied to late onset hereditary Ataxia, they said. SCA6 was negative, so mine was ruled ILOCA. That always surprised me, because my mother had late onset Ataxia as well. So now I may be SCA7???

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**Author:** ![Beryl\_Park](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.livingwithataxia.org/beryl_park/32/5716_2.png) [@Beryl\_Park](https://forum.livingwithataxia.org/u/Beryl_Park)\
**Post date:** [August 28, 2018, 9:53am UTC](https://forum.livingwithataxia.org/t/spg7-maybe-the-cause-of-late-onset-ataxia/6936/3 "2018-08-28T09:53:04Z")

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🤔 I read the conclusion. This test should be considered a priority for people diagnosed with ‘late onset pure ataxia’ 🤔 So, this is a question for your Neurologist 🙂 xB

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**Author:** ![Alan\_T](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.livingwithataxia.org/alan_t/32/31_2.png) [@Alan\_T](https://forum.livingwithataxia.org/u/Alan_T)\
**Post date:** [October 27, 2018, 4:56pm UTC](https://forum.livingwithataxia.org/t/spg7-maybe-the-cause-of-late-onset-ataxia/6936/4 "2018-10-27T16:56:23Z")

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Very True  
It seems that there is alot more to this, although we have be mindful that as research progresses - it will “uncover” differing and new ways within the diagnosis process