Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich’s ataxia YG8R mouse model . Dr. Yuxi Shan, Dr. Robert A Schoenfeld, Genki Hayashi, Dr. Eleonora Napoli, Dr. Tasuku Akiyama, Dr. Mirela Iodi-Carstens, Dr. Earl E. Carstens, Dr. Mark A. Pook, and Dr. Gino Cortopassi. Antioxidants & Redox Signaling. -Not available-, ahead of print. doi:10.1089/ars.2012.4537.
"Frataxin expression was significantly correlated with Nrf2 expression"
Keywords: Oxidative stress, Dorsal Root Ganglion (DRG) neurons, transcripts encoding antioxidants, peroxiredoxins, glutaredoxins, glutathione-S-transferase, antioxidant transcription factor Nrf2, frataxin, thioredoxin reductase.
"Frataxin expression was significantly correlated with Nrf2 expression"
Keywords: Oxidative stress, Dorsal Root Ganglion (DRG) neurons, transcripts encoding antioxidants, peroxiredoxins, glutaredoxins, glutathione-S-transferase, antioxidant transcription factor Nrf2, frataxin, thioredoxin reductase.