Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia (CStDCSAtaxia) Identifier: NCT03120013 First received: April 14, 2017

Neurodegenerative cerebellar ataxias represent a group of disabling disorders for which we currently lack effective therapies. Cerebellar transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been demonstrated to modulate cerebellar excitability and improve symptoms in patients with cerebellar ataxias. In this randomized, double-blind, sham-controlled study, the investigators will evaluate whether a two-weeks’ treatment with cerebellar anodal tDCS and spinal cathodal tDCS can improve symptoms in patients with neurodegenerative cerebellar ataxia and can modulate cerebello-motor connectivity, at short and long term.

Ataxia, Cerebellar, Cerebellar Ataxia, Spinocerebellar Ataxias, Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia 3, Spinocerebellar Degenerations, Friedreich Ataxia, Ataxia With Oculomotor Apraxia, Multiple System Atrophy.
Device: Anodal cerebellar and cathodal spinal tDCS, Device: Sham cerebellar and sham spinal tDCS.

Italy, AO Spedali Civili, Brescia, BS, Italy, 25100


More interesting and hopeful news Alan. They seem to be coming at this in all
different ways.

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Yes, more good news.

IMHO, there is alot going on that doesnt get communicated to the people it effects (the patient)

(this lack of communication is a subject, I have mentioned to pharma on many occasions at many Global events - although it is acknowledged, things move very slowly in the medical world)

all the best to you and your family

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Agreed Alan, it is very hard to find information out there. That’s why every morning I get up I come onto

this forum hoping you have posted more information on research. Treatment may never come but all we

look for is a bit of hope and that is what you give us. When Cassie was diagnosed almost 5 years ago in the

Southern General in Glasgow we were told she had Sca2 and nothing else. No information, possible treatment

or ideas on food or exercise. A little hope can make a person so much stronger.


Very interesting and fascinating. thanks for sharing.